Category Archives: Medical Technologies

Sprint Bioscience Strengthens Its Cancer Metabolism Portfolio

Sprint Bioscience, a Swedish company developing oncology therapeutics targeting cancer metabolism, announced today that it has raised money to strengthen its drug discovery portfolio.

The investment by Första Entreprenörsfonden and Almi Invest will enable the company to continue to build a pipeline of drug discovery projects within cancer metabolism.

“We are investing in Sprint Bioscience because we consider their entrepreneurial drive and their particular skills in drug development to be key success factors for the changing environment of the future pharmaceutical industry. Sprint Bioscience’s business strategy involves out-licensing or collaborating at an early stage of drug discovery to ensure that projects are developed with a focus on current and relevant market needs,” says Rune Nordlander, partner at Första Entreprenörsfonden.

Sprint Bioscience is a company founded by experienced drug hunters with an ambition to improve the drug discovery process. “We believe in small organisations with effective working procedures and collaborations throughout the sector,” says the company’s CEO and co-founder, Dr. Anders Ã…berg.

“Sprint Bioscience has developed an efficient, fragment-based drug discovery (FBDD) platform that can take parallel projects from initial idea to active molecules tested in cell-based systems in a very short time” Anders Ã…berg continues. Our goal is to align the early phase in the laboratory with pharmaceutical companies’ needs.

Targeting the metabolism in tumours provides exciting opportunities to develop drug therapies with novel mechanisms of action. This could be used to overcome the resistance that many cancer cells develop to current treatments.

Via EPR Network
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Advanced Liquid Logic Licenses Patents, Creates Collaboration With CEA-Leti

Advanced Liquid Logic announced today that it has signed a license and collaboration agreement with the French research institute CEA-Leti. The agreement provides Advanced Liquid Logic with worldwide exclusive access to CEA’s portfolio of patents related to digital microfluidics.

Advanced Liquid Logic co-founder and Dr. Michael Pollack said, “This agreement puts our company in a clearly dominant position with respect to the intellectual property surrounding digital microfluidics.” Co-founder Dr. Vamsee Pamula added, “the accompanying collaboration with a very active and highly competent group of researchers will provide us with key technical resources to help address both today’s and tomorrow’s technology challenges.” Advanced Liquid Logic has set up a subsidiary company in Grenoble, France to help manage the collaboration and to provide an initial position to address market opportunities in Europe. CEA-Leti employee Dr. Cyril Delattre will join the company and manage Advanced Liquid Logic’s French subsidiary.

“The combination of Advanced Liquid Logic’s intellectual property position and their readiness for market made them the ideal partner,” said Dr. Laurent Malier, CEO Leti. “We expect that our complementary skills, expertise and intellectual property will be very useful going forward. This partnership with Advanced Liquid Logic offers an industrial solution that will help us develop applications bases on microfluidics for many sectors”.

Advanced Liquid Logic previously acquired intellectual property from Nanolytics and Core Microsolutions. The company now owns or controls over 45 issued patents related to their proprietary, electrowetting-based digital microfluidic technology.

About Advanced Liquid Logic
Advanced Liquid Logic, headquartered in Research Triangle Park, North Carolina, is commercializing its proprietary “Digital Microfluidics” technology in a spectrum of life sciences and clinical diagnostics applications. Digital microfluidics enables precise and flexible manipulation of microdroplets using electrical fields and therefore avoids the need for pumps, valves or microchannels required by competing technologies. For more information please visit http://www.liquid-logic.com/

About CEA-Leti
CEA is a French research and technology organization, with activities in four main areas: energy, information technologies, healthcare technologies and defence and security. Within CEA, the Laboratory for Electronics & Information Technology (CEA-Leti) works with companies in order to increase their competitiveness through technological innovation and transfers. CEA-Leti is focused on micro and nanotechnologies and their applications, from wireless devices and systems, to biology and healthcare or photonics. Nanoelectronics and microsystems (MEMS) are at the core of its activities. As a major player in MINATEC campus, CEA-Leti operates 8,000-m² state-of-the-art clean rooms, on 24/7 mode, on 200mm and 300mm wafer standards. With 1,400 employees, CEA-Leti trains more than 190 Ph.D. students and hosts 200 assignees from partner companies. Strongly committed to the creation of value for the industry, CEA-Leti puts a strong emphasis on intellectual property and owns more than 1,700 patent families.
Visit www.leti.fr.

Via EPR Network
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CodeLink business assets have been transferred under the agreement between Applied Microarrays and GE Healthcare

Applied Microarrays, Inc announced today the completion of Applied Microarrays’ purchase of certain assets of GE Healthcare’s CodeLinkâ„¢ Gene Expression Bioarray System. Under the terms of the agreement, Applied Microarrays, Inc acquires certain equipment, inventory, licenses and assigned contracts associated with the CodeLink platform. Financial terms were not disclosed.

The transaction enables Applied Microarrays to provide CodeLink users with continued and uninterrupted access to the industry-leading gene expression platform as Applied Microarrays, Inc continues to develop, market, distribute, sell, and support the existing CodeLink catalogue of whole genome expression arrays, Codelink custom arrays and Codelink inside arrays.

Alastair Malcolm, president and chief executive officer of Applied Microarrays, said, “We’re pleased to now have a unique opportunity to launch our company with a full range of microarray design, development, and manufacturing competencies and at the same time ensure a seamless transition for customers.

Eric Roman, General Manager Genomic Sciences, GE Healthcare, said, “There has been strong demand from CodeLink customers to keep these products in the marketplace. We’re delighted to have found a way for our customers to continue working with one of the best gene expression platforms available.”

“The CodeLink platform is customer-proven over several years, notably demonstrating world-class technical performance in the FDA-led MicroArray Quality Control project,” Malcolm said. Applied Microarrays is immediately opening the CodeLink platform to the microarray community for new applications development, offering customers the opportunity to place their unique custom array content on to a robust, proven platform which can be manufactured in high volume.

Applied Microarrays aims to be a leading contract manufacturer of microarrays, of any type, for any customer, with no limitations on substrate material or spotted fluid. “We are fortunate in this regard to have acquired an intact high-capacity microarray spotting facility, employing Six Sigma techniques since its inception to produce leadership quality products,” Malcolm said.

About Applied Microarrays, Inc.
Applied Microarrays is a new company headquartered in Tempe, Arizona. Using the microarray assets acquired from GE, and staffed with experts who developed the CodeLink platform and manufacturing capabilities, the company will specialize in contract development and manufacturing of custom microarrays of all types. The company will additionally continue to offer the CodeLink family of gene expression arrays, and customer-specified subsets of that content on multi-array formats. Our vision is to be the microarray partner of choice for focused “omics” research, and the leading high-volume contract manufacturer for research and diagnostic arrays.

About GE Healthcare
GE Healthcare provides transformational medical technologies and services that are shaping a new age of patient care. GE Healthcare’s expertise in medical imaging and information technologies, medical diagnostics, patient monitoring systems, performance improvement, drug discovery, and biopharmaceutical manufacturing technologies is helping clinicians around the world re-imagine new ways to predict, diagnose, inform, treat and monitor disease, so patients can live their lives to the fullest.

GE Healthcare’s broad range of products and services enable healthcare providers to better diagnose and treat cancer, heart disease, neurological diseases and other conditions earlier. GE Healthcare’s vision for the future is to enable a new “early health” model of care focused on earlier diagnosis, pre-symptomatic disease detection and disease prevention. Headquartered in the United Kingdom, GE Healthcare is a $17 billion unit of General Electric Company (NYSE: GE). Worldwide, GE Healthcare employs more than 46,000 people committed to serving healthcare professionals and their patients in more than 100 countries.

Via EPR Network
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